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Specific threonine-4 phosphorylation and function of RNA polymerase II CTD during M phase progression

Dynamic phosphorylation of Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7 heptad-repeats in the C-terminal domain (CTD) of the large subunit coordinates progression of RNA polymerase (Pol) II through the transcription cycle. Here, we describe an M phase-specific form of Pol II phosphorylated at Thr4, but not at...

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Detalles Bibliográficos
Autores principales: Hintermair, Corinna, Voß, Kirsten, Forné, Ignasi, Heidemann, Martin, Flatley, Andrew, Kremmer, Elisabeth, Imhof, Axel, Eick, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893663/
https://www.ncbi.nlm.nih.gov/pubmed/27264542
http://dx.doi.org/10.1038/srep27401