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MCRS1 associates with cytoplasmic dynein and mediates pericentrosomal material recruitment

MCRS1 is involved in multiple cellular activities, including mitotic spindle assembly, mTOR signaling and tumorigenesis. Although MCRS1 has been reported to bind to the dynein regulator NDE1, a functional interaction between MCRS1 and cytoplasmic dynein remains unaddressed. Here, we demonstrate that...

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Detalles Bibliográficos
Autores principales: Lee, Si-Hyung, Lee, Mi-Sun, Choi, Tae-Ik, Hong, Hyowon, Seo, Jun-Young, Kim, Cheol-Hee, Kim, Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893664/
https://www.ncbi.nlm.nih.gov/pubmed/27263857
http://dx.doi.org/10.1038/srep27284