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Distinct Defects in Synaptic Differentiation of Neocortical Neurons in Response to Prenatal Valproate Exposure

Autism spectrum disorders (ASDs) are a heterogeneous group of neurodevelopmental disorders characterized by impairments in social interactions and stereotyped behaviors. Valproic acid (VPA) is frequently used to treat epilepsy and bipolar disorders. When taken during pregnancy, VPA increases the ris...

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Detalles Bibliográficos
Autores principales: Iijima, Yoko, Behr, Katharina, Iijima, Takatoshi, Biemans, Barbara, Bischofberger, Josef, Scheiffele, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893673/
https://www.ncbi.nlm.nih.gov/pubmed/27264355
http://dx.doi.org/10.1038/srep27400