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A metabolomics cell-based approach for anticipating and investigating drug-induced liver injury
In preclinical stages of drug development, anticipating potential adverse drug effects such as toxicity is an important issue for both saving resources and preventing public health risks. Current in vitro cytotoxicity tests are restricted by their predictive potential and their ability to provide me...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893700/ https://www.ncbi.nlm.nih.gov/pubmed/27265840 http://dx.doi.org/10.1038/srep27239 |