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High-contrast grating resonators for label-free detection of disease biomarkers

A label-free optical biosensor is described that employs a silicon-based high-contrast grating (HCG) resonator with a spectral linewidth of ~500 pm that is sensitive to ligand-induced changes in surface properties. The device is used to generate thermodynamic and kinetic data on surface-attached ant...

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Detalles Bibliográficos
Autores principales: Sun, Tianbo, Kan, Shu, Marriott, Gerard, Chang-Hasnain, Connie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893738/
https://www.ncbi.nlm.nih.gov/pubmed/27265624
http://dx.doi.org/10.1038/srep27482