Folliculin directs the formation of a Rab34–RILP complex to control the nutrient‐dependent dynamic distribution of lysosomes

The spatial distribution of lysosomes is important for their function and is, in part, controlled by cellular nutrient status. Here, we show that the lysosome associated Birt–Hoge–Dubé (BHD) syndrome renal tumour suppressor folliculin (FLCN) regulates this process. FLCN promotes the peri‐nuclear clu...

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Detalles Bibliográficos
Autores principales: Starling, Georgina P, Yip, Yan Y, Sanger, Anneri, Morton, Penny E, Eden, Emily R, Dodding, Mark P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893818/
https://www.ncbi.nlm.nih.gov/pubmed/27113757
http://dx.doi.org/10.15252/embr.201541382

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893818/
https://www.ncbi.nlm.nih.gov/pubmed/27113757
http://dx.doi.org/10.15252/embr.201541382

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