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Orthogonal matrix factorization enables integrative analysis of multiple RNA binding proteins

Motivation: RNA binding proteins (RBPs) play important roles in post-transcriptional control of gene expression, including splicing, transport, polyadenylation and RNA stability. To model protein–RNA interactions by considering all available sources of information, it is necessary to integrate the r...

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Detalles Bibliográficos
Autores principales: Stražar, Martin, Žitnik, Marinka, Zupan, Blaž, Ule, Jernej, Curk, Tomaž
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894278/
https://www.ncbi.nlm.nih.gov/pubmed/26787667
http://dx.doi.org/10.1093/bioinformatics/btw003