Design of a Split Intein with Exceptional Protein Splicing Activity

[Image: see text] Protein trans-splicing (PTS) by split inteins has found widespread use in chemical biology and biotechnology. Herein, we describe the use of a consensus design approach to engineer a split intein with enhanced stability and activity that make it more robust than any known PTS syste...

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Detalles Bibliográficos
Autores principales: Stevens, Adam J., Brown, Zachary Z., Shah, Neel H., Sekar, Giridhar, Cowburn, David, Muir, Tom W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894280/
https://www.ncbi.nlm.nih.gov/pubmed/26854538
http://dx.doi.org/10.1021/jacs.5b13528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894280/
https://www.ncbi.nlm.nih.gov/pubmed/26854538
http://dx.doi.org/10.1021/jacs.5b13528

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