Simultaneous quantification of mitochondrial DNA copy number and deletion ratio: A multiplex real-time PCR assay

Mitochondrial dysfunction is implicated in a vast array of diseases and conditions, such as Alzheimer's disease, cancer, and aging. Alterations in mitochondrial DNA (mtDNA) may provide insight into the processes that either initiate or propagate this dysfunction. Here, we describe a unique mult...

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Detalles Bibliográficos
Autores principales: Phillips, Nicole R., Sprouse, Marc L., Roby, Rhonda K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894387/
https://www.ncbi.nlm.nih.gov/pubmed/24463429
http://dx.doi.org/10.1038/srep03887

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894387/
https://www.ncbi.nlm.nih.gov/pubmed/24463429
http://dx.doi.org/10.1038/srep03887

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