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Repurpose terbutaline sulfate for amyotrophic lateral sclerosis using electronic medical records

Prediction of new disease indications for approved drugs by computational methods has been based largely on the genomics signatures of drugs and diseases. We propose a method for drug repositioning that uses the clinical signatures extracted from over 13 years of electronic medical records from a te...

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Detalles Bibliográficos
Autores principales: Paik, Hyojung, Chung, Ah-Young, Park, Hae-Chul, Park, Rae Woong, Suk, Kyoungho, Kim, Jihyun, Kim, Hyosil, Lee, KiYoung, Butte, Atul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894399/
https://www.ncbi.nlm.nih.gov/pubmed/25739475
http://dx.doi.org/10.1038/srep08580