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Oleanolic acid acrylate elicits antidepressant-like effect mediated by 5-HT(1A) receptor

The development of new drugs for the treatment of depression is strategic to achieving clinical needs of patients. This study evaluates antidepressant-like effect and neural mechanisms of four oleanolic acid derivatives i.e. acrylate (D1), methacrylate (D2), methyl fumarate (D3) and ethyl fumarate (...

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Detalles Bibliográficos
Autores principales: Fajemiroye, James O., Polepally, Prabhakar R., Chaurasiya, Narayan D., Tekwani, Babu L., Zjawiony, Jordan K., Costa, Elson A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894409/
https://www.ncbi.nlm.nih.gov/pubmed/26199018
http://dx.doi.org/10.1038/srep11582