Toward a more accurate view of human B-cell repertoire by next-generation sequencing, unbiased repertoire capture and single-molecule barcoding

B-cell repertoire analysis using next-generation sequencing has become a valuable tool for interrogating the genetic record of humoral response to infection. However, key obstacles such as low throughput, short read length, high error rate, and undetermined bias of multiplex PCR method have hindered...

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Detalles Bibliográficos
Autores principales: He, Linling, Sok, Devin, Azadnia, Parisa, Hsueh, Jessica, Landais, Elise, Simek, Melissa, Koff, Wayne C., Poignard, Pascal, Burton, Dennis R., Zhu, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894419/
https://www.ncbi.nlm.nih.gov/pubmed/25345460
http://dx.doi.org/10.1038/srep06778

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894419/
https://www.ncbi.nlm.nih.gov/pubmed/25345460
http://dx.doi.org/10.1038/srep06778

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