Channelrhodopsin2 Current During the Action Potential: “Optical AP Clamp” and Approximation

The most widely used optogenetic tool, Channelrhodopsin2 (ChR2), is both light- and voltage-sensitive. A light-triggered action potential or light-driven perturbations of ongoing electrical activity provide instant voltage feedback, shaping ChR2 current. Therefore, depending on the cell type and the...

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Detalles Bibliográficos
Autores principales: Entcheva, Emilia, Williams, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894422/
https://www.ncbi.nlm.nih.gov/pubmed/25060859
http://dx.doi.org/10.1038/srep05838

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894422/
https://www.ncbi.nlm.nih.gov/pubmed/25060859
http://dx.doi.org/10.1038/srep05838

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