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Argonaute CLIP-Seq reveals miRNA targetome diversity across tissue types

To date, analyses of individual targets have provided evidence of a miRNA targetome that extends beyond the boundaries of messenger RNAs (mRNAs) and can involve non-Watson-Crick base pairing in the miRNA seed region. Here we report our findings from analyzing 34 Argonaute HITS-CLIP datasets from sev...

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Detalles Bibliográficos
Autores principales: Clark, Peter M., Loher, Phillipe, Quann, Kevin, Brody, Jonathan, Londin, Eric R., Rigoutsos, Isidore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894423/
https://www.ncbi.nlm.nih.gov/pubmed/25103560
http://dx.doi.org/10.1038/srep05947