Discerning mechanistically rewired biological pathways by cumulative interaction heterogeneity statistics

Changes in response of a biological pathway could be a consequence of either pathway rewiring, changed input, or a combination of both. Most pathway analysis methods are not designed for mechanistic rewiring such as regulatory element variations. This limits our understanding of biological pathway e...

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Detalles Bibliográficos
Autores principales: Cotton, Travis B., Nguyen, Hien H., Said, Joseph I., Ouyang, Zhengyu, Zhang, Jinfa, Song, Mingzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894439/
https://www.ncbi.nlm.nih.gov/pubmed/25921728
http://dx.doi.org/10.1038/srep09634

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894439/
https://www.ncbi.nlm.nih.gov/pubmed/25921728
http://dx.doi.org/10.1038/srep09634

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