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Discerning mechanistically rewired biological pathways by cumulative interaction heterogeneity statistics
Changes in response of a biological pathway could be a consequence of either pathway rewiring, changed input, or a combination of both. Most pathway analysis methods are not designed for mechanistic rewiring such as regulatory element variations. This limits our understanding of biological pathway e...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894439/ https://www.ncbi.nlm.nih.gov/pubmed/25921728 http://dx.doi.org/10.1038/srep09634 |