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Quantifying Nucleoporin Stoichiometry Inside Single Nuclear Pore Complexes In vivo

The nuclear pore complex (NPC) is one of the largest supramolecular structures in eukaryotic cells. Its octagonal ring-scaffold perforates the nuclear envelope and features a unique molecular machinery that regulates nucleocytoplasmic transport. NPCs are composed of ~30 different nucleoporins (Nups)...

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Detalles Bibliográficos
Autores principales: Mi, Lan, Goryaynov, Alexander, Lindquist, Andre, Rexach, Michael, Yang, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894440/
https://www.ncbi.nlm.nih.gov/pubmed/25797490
http://dx.doi.org/10.1038/srep09372