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Nicotinic Acid is a Common Regulator of Heat-Sensing TRPV1-4 Ion Channels

Nicotinic acid (NA, a.k.a. vitamin B3 or niacin) can reduce blood cholesterol and low-density lipoproteins whereas increase high-density lipoproteins. However, when NA is used to treat dyslipidemias, it causes a strong side effect of cutaneous vasodilation, commonly called flushing. A recent study s...

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Detalles Bibliográficos
Autores principales: Ma, Linlin, Lee, Bo Hyun, Clifton, Heather, Schaefer, Saul, Zheng, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894441/
https://www.ncbi.nlm.nih.gov/pubmed/25752528
http://dx.doi.org/10.1038/srep08906