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Novel Antiplatelet Activity of Minocycline Involves Inhibition of MLK3-p38 Mitogen Activated Protein Kinase Axis

Platelets play an essential role in hemostasis and wound healing by facilitating thrombus formation at sites of injury. Platelets also mediate inflammation and contain several pro-inflammatory molecules including cytokines and chemokines that mediate leukocyte recruitment and activation. Not surpris...

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Detalles Bibliográficos
Autores principales: Jackson, Joseph W., Singh, Meera V., Singh, Vir B., Jones, Letitia D., Davidson, Gregory A., Ture, Sara, Morrell, Craig N., Schifitto, Giovanni, Maggirwar, Sanjay B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894566/
https://www.ncbi.nlm.nih.gov/pubmed/27270236
http://dx.doi.org/10.1371/journal.pone.0157115