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Novel Antiplatelet Activity of Minocycline Involves Inhibition of MLK3-p38 Mitogen Activated Protein Kinase Axis
Platelets play an essential role in hemostasis and wound healing by facilitating thrombus formation at sites of injury. Platelets also mediate inflammation and contain several pro-inflammatory molecules including cytokines and chemokines that mediate leukocyte recruitment and activation. Not surpris...
Autores principales: | Jackson, Joseph W., Singh, Meera V., Singh, Vir B., Jones, Letitia D., Davidson, Gregory A., Ture, Sara, Morrell, Craig N., Schifitto, Giovanni, Maggirwar, Sanjay B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894566/ https://www.ncbi.nlm.nih.gov/pubmed/27270236 http://dx.doi.org/10.1371/journal.pone.0157115 |
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