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RAB-10 Promotes EHBP-1 Bridging of Filamentous Actin and Tubular Recycling Endosomes

EHBP-1 (Ehbp1) is a conserved regulator of endocytic recycling, acting as an effector of small GTPases including RAB-10 (Rab10). Here we present evidence that EHBP-1 associates with tubular endosomal phosphatidylinositol-4,5-bisphosphate [PI(4,5)P2] enriched membranes through an N-terminal C2-like (...

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Detalles Bibliográficos
Autores principales: Wang, Peixiang, Liu, Hang, Wang, Yu, Liu, Ou, Zhang, Jing, Gleason, Adenrele, Yang, Zhenrong, Wang, Hui, Shi, Anbing, Grant, Barth D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894640/
https://www.ncbi.nlm.nih.gov/pubmed/27272733
http://dx.doi.org/10.1371/journal.pgen.1006093