Genetic Analysis Reveals a Hierarchy of Interactions between Polycystin-Encoding Genes and Genes Controlling Cilia Function during Left-Right Determination

During mammalian development, left-right (L-R) asymmetry is established by a cilia-driven leftward fluid flow within a midline embryonic cavity called the node. This ‘nodal flow’ is detected by peripherally-located crown cells that each assemble a primary cilium which contain the putative Ca(2+) cha...

Descripción completa

Detalles Bibliográficos
Autores principales: Grimes, Daniel T., Keynton, Jennifer L., Buenavista, Maria T., Jin, Xingjian, Patel, Saloni H., Kyosuke, Shinohara, Vibert, Jennifer, Williams, Debbie J., Hamada, Hiroshi, Hussain, Rohanah, Nauli, Surya M., Norris, Dominic P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894641/
https://www.ncbi.nlm.nih.gov/pubmed/27272319
http://dx.doi.org/10.1371/journal.pgen.1006070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894641/
https://www.ncbi.nlm.nih.gov/pubmed/27272319
http://dx.doi.org/10.1371/journal.pgen.1006070

Ejemplares similares