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CRISPR-Cas and Restriction-Modification Act Additively against Conjugative Antibiotic Resistance Plasmid Transfer in Enterococcus faecalis

Enterococcus faecalis is an opportunistic pathogen and a leading cause of nosocomial infections. Conjugative pheromone-responsive plasmids are narrow-host-range mobile genetic elements (MGEs) that are rapid disseminators of antibiotic resistance in the faecalis species. Clustered regularly interspac...

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Detalles Bibliográficos
Autores principales: Price, Valerie J., Huo, Wenwen, Sharifi, Ardalan, Palmer, Kelli L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894674/
https://www.ncbi.nlm.nih.gov/pubmed/27303749
http://dx.doi.org/10.1128/mSphere.00064-16