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IS26-Mediated Formation of Transposons Carrying Antibiotic Resistance Genes

The IS26 transposase, Tnp26, catalyzes IS26 movement to a new site and deletion or inversion of adjacent DNA via a replicative route. The intramolecular deletion reaction produces a circular molecule consisting of a DNA segment and a single IS26, which we call a translocatable unit or TU. Recently,...

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Detalles Bibliográficos
Autores principales: Harmer, Christopher J., Hall, Ruth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894685/
https://www.ncbi.nlm.nih.gov/pubmed/27303727
http://dx.doi.org/10.1128/mSphere.00038-16