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In Vivo GFP Knockdown by Cationic Nanogel-siRNA Polyplexes

RNA interference (RNAi) is a powerful tool to treat diseases and elucidate target gene function. Prior to clinical implementation, however, challenges including the safe, efficient and targeted delivery of siRNA must be addressed. Here, we report cationic nanogel nanostructured polymers (NSPs) prepa...

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Detalles Bibliográficos
Autores principales: Shrivats, Arun R., Mishina, Yuji, Averick, Saadyah, Matyjaszewski, Krzysztof, Hollinger, Jeffrey O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894740/
https://www.ncbi.nlm.nih.gov/pubmed/27280121
http://dx.doi.org/10.3390/bioengineering2030160