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In Vivo GFP Knockdown by Cationic Nanogel-siRNA Polyplexes
RNA interference (RNAi) is a powerful tool to treat diseases and elucidate target gene function. Prior to clinical implementation, however, challenges including the safe, efficient and targeted delivery of siRNA must be addressed. Here, we report cationic nanogel nanostructured polymers (NSPs) prepa...
Autores principales: | Shrivats, Arun R., Mishina, Yuji, Averick, Saadyah, Matyjaszewski, Krzysztof, Hollinger, Jeffrey O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894740/ https://www.ncbi.nlm.nih.gov/pubmed/27280121 http://dx.doi.org/10.3390/bioengineering2030160 |
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