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Notch1 regulated autophagy controls survival and suppressor activity of activated murine T-regulatory cells

Cell survival is one of several processes regulated by the Notch pathway in mammalian cells. Here we report functional outcomes of non-nuclear Notch signaling to activate autophagy, a conserved cellular response to nutrient stress, regulating survival in murine natural T-regulatory cells (Tregs), an...

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Detalles Bibliográficos
Autores principales: Marcel, Nimi, Sarin, Apurva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894756/
https://www.ncbi.nlm.nih.gov/pubmed/27267497
http://dx.doi.org/10.7554/eLife.14023