Synchronization of endothelial Dll4-Notch dynamics switch blood vessels from branching to expansion

Formation of a regularly branched blood vessel network is crucial in development and physiology. Here we show that the expression of the Notch ligand Dll4 fluctuates in individual endothelial cells within sprouting vessels in the mouse retina in vivo and in correlation with dynamic cell movement in...

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Detalles Bibliográficos
Autores principales: Ubezio, Benedetta, Blanco, Raquel Agudo, Geudens, Ilse, Stanchi, Fabio, Mathivet, Thomas, Jones, Martin L, Ragab, Anan, Bentley, Katie, Gerhardt, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Computational and Systems Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894757/
https://www.ncbi.nlm.nih.gov/pubmed/27074663
http://dx.doi.org/10.7554/eLife.12167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894757/
https://www.ncbi.nlm.nih.gov/pubmed/27074663
http://dx.doi.org/10.7554/eLife.12167

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