An Intronic Flk1 Enhancer Directs Arterial-Specific Expression via RBPJ-Mediated Venous Repression

OBJECTIVE—: The vascular endothelial growth factor (VEGF) receptor Flk1 is essential for vascular development, but the signaling and transcriptional pathways by which its expression is regulated in endothelial cells remain unclear. Although previous studies have identified 2 Flk1 regulatory enhancer...

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Detalles Bibliográficos
Autores principales: Becker, Philipp W., Sacilotto, Natalia, Nornes, Svanhild, Neal, Alice, Thomas, Max O., Liu, Ke, Preece, Chris, Ratnayaka, Indrika, Davies, Benjamin, Bou-Gharios, George, De Val, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2016
Materias:
Basic Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894770/
https://www.ncbi.nlm.nih.gov/pubmed/27079877
http://dx.doi.org/10.1161/ATVBAHA.116.307517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894770/
https://www.ncbi.nlm.nih.gov/pubmed/27079877
http://dx.doi.org/10.1161/ATVBAHA.116.307517

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