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An Intronic Flk1 Enhancer Directs Arterial-Specific Expression via RBPJ-Mediated Venous Repression
OBJECTIVE—: The vascular endothelial growth factor (VEGF) receptor Flk1 is essential for vascular development, but the signaling and transcriptional pathways by which its expression is regulated in endothelial cells remain unclear. Although previous studies have identified 2 Flk1 regulatory enhancer...
Autores principales: | Becker, Philipp W., Sacilotto, Natalia, Nornes, Svanhild, Neal, Alice, Thomas, Max O., Liu, Ke, Preece, Chris, Ratnayaka, Indrika, Davies, Benjamin, Bou-Gharios, George, De Val, Sarah |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894770/ https://www.ncbi.nlm.nih.gov/pubmed/27079877 http://dx.doi.org/10.1161/ATVBAHA.116.307517 |
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