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Killing of Escherichia coli by Crohn's Disease Monocyte-derived Macrophages and Its Enhancement by Hydroxychloroquine and Vitamin D

BACKGROUND: Crohn's disease (CD) is associated with defective innate immunity, including impaired neutrophil chemotaxis, and mucosal invasion by bacteria, particularly adherent and invasive Escherichia coli that replicate inside macrophage phagolysosomes. We compared CD and healthy control (HC)...

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Detalles Bibliográficos
Autores principales: Flanagan, Paul K., Chiewchengchol, Direkrit, Wright, Helen L., Edwards, Steven W., Alswied, Abdullah, Satsangi, Jack, Subramanian, Sreedhar, Rhodes, Jonathan M., Campbell, Barry J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894789/
https://www.ncbi.nlm.nih.gov/pubmed/25839777
http://dx.doi.org/10.1097/MIB.0000000000000387