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Killing of Escherichia coli by Crohn's Disease Monocyte-derived Macrophages and Its Enhancement by Hydroxychloroquine and Vitamin D
BACKGROUND: Crohn's disease (CD) is associated with defective innate immunity, including impaired neutrophil chemotaxis, and mucosal invasion by bacteria, particularly adherent and invasive Escherichia coli that replicate inside macrophage phagolysosomes. We compared CD and healthy control (HC)...
Autores principales: | Flanagan, Paul K., Chiewchengchol, Direkrit, Wright, Helen L., Edwards, Steven W., Alswied, Abdullah, Satsangi, Jack, Subramanian, Sreedhar, Rhodes, Jonathan M., Campbell, Barry J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894789/ https://www.ncbi.nlm.nih.gov/pubmed/25839777 http://dx.doi.org/10.1097/MIB.0000000000000387 |
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