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β(3) Integrin Promotes Long-Lasting Activation and Polarization of Vascular Endothelial Growth Factor Receptor 2 by Immobilized Ligand

OBJECTIVE—: During neovessel formation, angiogenic growth factors associate with the extracellular matrix. These immobilized factors represent a persistent stimulus for the otherwise quiescent endothelial cells (ECs), driving directional EC migration and proliferation and leading to new blood vessel...

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Detalles Bibliográficos
Autores principales: Ravelli, Cosetta, Grillo, Elisabetta, Corsini, Michela, Coltrini, Daniela, Presta, Marco, Mitola, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894810/
https://www.ncbi.nlm.nih.gov/pubmed/26293466
http://dx.doi.org/10.1161/ATVBAHA.115.306230