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Choreographing the Double Strand Break Response: Ubiquitin and SUMO Control of Nuclear Architecture

The cellular response to DNA double strand breaks (DSBs) is a multifaceted signaling program that centers on post-translational modifications including phosphorylation, ubiquitylation and SUMOylation. In this review we discuss how ubiquitin and SUMO orchestrate the recognition of DSBs and explore ho...

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Detalles Bibliográficos
Autores principales: Harding, Shane M., Greenberg, Roger A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894868/
https://www.ncbi.nlm.nih.gov/pubmed/27375678
http://dx.doi.org/10.3389/fgene.2016.00103