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Choreographing the Double Strand Break Response: Ubiquitin and SUMO Control of Nuclear Architecture
The cellular response to DNA double strand breaks (DSBs) is a multifaceted signaling program that centers on post-translational modifications including phosphorylation, ubiquitylation and SUMOylation. In this review we discuss how ubiquitin and SUMO orchestrate the recognition of DSBs and explore ho...
Autores principales: | Harding, Shane M., Greenberg, Roger A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894868/ https://www.ncbi.nlm.nih.gov/pubmed/27375678 http://dx.doi.org/10.3389/fgene.2016.00103 |
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