α-Mangostin Inhibits α-Synuclein-Induced Microglial Neuroinflammation and Neurotoxicity

Microglia-mediated neuroinflammation induced by α-synuclein in the substantianigra likely either initiates or aggravates nigral neuro degeneration in Parkinson’s disease (PD). We aimed to explore the effects of α-mangostin (α-M), a polyphenolicxanthone derivative from mangosteen on α-synuclein-stimu...

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Detalles Bibliográficos
Autores principales: Hu, Zhaoyang, Wang, Wei, Ling, Jing, Jiang, Chunming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894924/
https://www.ncbi.nlm.nih.gov/pubmed/27002719
http://dx.doi.org/10.1007/s10571-015-0264-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894924/
https://www.ncbi.nlm.nih.gov/pubmed/27002719
http://dx.doi.org/10.1007/s10571-015-0264-9

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