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Modulatory effects of α7 nAChRs on the immune system and its relevance for CNS disorders

The clinical development of selective alpha-7 nicotinic acetylcholine receptor (α7 nAChR) agonists has hitherto been focused on disorders characterized by cognitive deficits (e.g., Alzheimer’s disease, schizophrenia). However, α7 nAChRs are also widely expressed by cells of the immune system and by...

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Detalles Bibliográficos
Autores principales: Kalkman, Hans O., Feuerbach, Dominik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894934/
https://www.ncbi.nlm.nih.gov/pubmed/26979166
http://dx.doi.org/10.1007/s00018-016-2175-4