Cargando…

klf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis

The heartbeat and blood flow signal to endocardial cell progenitors through mechanosensitive proteins that modulate the genetic program controlling heart valve morphogenesis. To date, the mechanism by which mechanical forces coordinate tissue morphogenesis is poorly understood. Here we use high-reso...

Descripción completa

Detalles Bibliográficos
Autores principales: Steed, Emily, Faggianelli, Nathalie, Roth, Stéphane, Ramspacher, Caroline, Concordet, Jean-Paul, Vermot, Julien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894956/
https://www.ncbi.nlm.nih.gov/pubmed/27221222
http://dx.doi.org/10.1038/ncomms11646