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klf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis
The heartbeat and blood flow signal to endocardial cell progenitors through mechanosensitive proteins that modulate the genetic program controlling heart valve morphogenesis. To date, the mechanism by which mechanical forces coordinate tissue morphogenesis is poorly understood. Here we use high-reso...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894956/ https://www.ncbi.nlm.nih.gov/pubmed/27221222 http://dx.doi.org/10.1038/ncomms11646 |