Cargando…
klf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis
The heartbeat and blood flow signal to endocardial cell progenitors through mechanosensitive proteins that modulate the genetic program controlling heart valve morphogenesis. To date, the mechanism by which mechanical forces coordinate tissue morphogenesis is poorly understood. Here we use high-reso...
Autores principales: | Steed, Emily, Faggianelli, Nathalie, Roth, Stéphane, Ramspacher, Caroline, Concordet, Jean-Paul, Vermot, Julien |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894956/ https://www.ncbi.nlm.nih.gov/pubmed/27221222 http://dx.doi.org/10.1038/ncomms11646 |
Ejemplares similares
-
Cardiac forces regulate zebrafish heart valve delamination by modulating Nfat signaling
por: Chow, Renee Wei-Yan, et al.
Publicado: (2022) -
Mechanically activated piezo channels modulate outflow tract valve development through the Yap1 and Klf2-Notch signaling axis
por: Duchemin, Anne-Laure, et al.
Publicado: (2019) -
Rac GTPase signaling in mechanotransduction during embryonic morphogenesis
por: Labouesse, Michel
Publicado: (2011) -
Integrin-α9 is required for fibronectin matrix assembly
during lymphatic valve morphogenesis
por: Bazigou, Eleni, et al.
Publicado: (2009) -
In Full Force. Mechanotransduction and Morphogenesis during Homeostasis and Tissue Regeneration
por: Tsata, Vasiliki, et al.
Publicado: (2020)