Stepwise phosphorylation of p65 promotes NF-κB activation and NK cell responses during target cell recognition

NF-κB is a key transcription factor that dictates the outcome of diverse immune responses. How NF-κB is regulated by multiple activating receptors that are engaged during natural killer (NK)-target cell contact remains undefined. Here we show that sole engagement of NKG2D, 2B4 or DNAM-1 is insuffici...

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Detalles Bibliográficos
Autores principales: Kwon, Hyung-Joon, Choi, Go-Eun, Ryu, Sangryeol, Kwon, Soon Jae, Kim, Sun Chang, Booth, Claire, Nichols, Kim E., Kim, Hun Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894962/
https://www.ncbi.nlm.nih.gov/pubmed/27221592
http://dx.doi.org/10.1038/ncomms11686

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894962/
https://www.ncbi.nlm.nih.gov/pubmed/27221592
http://dx.doi.org/10.1038/ncomms11686

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