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Stepwise phosphorylation of p65 promotes NF-κB activation and NK cell responses during target cell recognition
NF-κB is a key transcription factor that dictates the outcome of diverse immune responses. How NF-κB is regulated by multiple activating receptors that are engaged during natural killer (NK)-target cell contact remains undefined. Here we show that sole engagement of NKG2D, 2B4 or DNAM-1 is insuffici...
Autores principales: | Kwon, Hyung-Joon, Choi, Go-Eun, Ryu, Sangryeol, Kwon, Soon Jae, Kim, Sun Chang, Booth, Claire, Nichols, Kim E., Kim, Hun Sik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894962/ https://www.ncbi.nlm.nih.gov/pubmed/27221592 http://dx.doi.org/10.1038/ncomms11686 |
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