Structure of the intact ATM/Tel1 kinase

The ataxia-telangiectasia mutated (ATM) protein is an apical kinase that orchestrates the multifaceted DNA-damage response. Normally, ATM kinase is in an inactive, homodimer form and is transformed into monomers upon activation. Besides a conserved kinase domain at the C terminus, ATM contains three...

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Detalles Bibliográficos
Autores principales: Wang, Xuejuan, Chu, Huanyu, Lv, Mengjuan, Zhang, Zhihui, Qiu, Shuwan, Liu, Haiyan, Shen, Xuetong, Wang, Weiwu, Cai, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894967/
https://www.ncbi.nlm.nih.gov/pubmed/27229179
http://dx.doi.org/10.1038/ncomms11655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894967/
https://www.ncbi.nlm.nih.gov/pubmed/27229179
http://dx.doi.org/10.1038/ncomms11655

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