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A method to rapidly create protein aggregates in living cells
The accumulation of protein aggregates is a common pathological hallmark of many neurodegenerative diseases. However, we do not fully understand how aggregates are formed or the complex network of chaperones, proteasomes and other regulatory factors involved in their clearance. Here, we report a che...
Autores principales: | Miyazaki, Yusuke, Mizumoto, Kota, Dey, Gautam, Kudo, Takamasa, Perrino, John, Chen, Ling-chun, Meyer, Tobias, Wandless, Thomas J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894968/ https://www.ncbi.nlm.nih.gov/pubmed/27229621 http://dx.doi.org/10.1038/ncomms11689 |
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