Store-independent modulation of Ca(2+) entry through Orai by Septin 7

Orai channels are required for store-operated Ca(2+) entry (SOCE) in multiple cell types. Septins are a class of GTP-binding proteins that function as diffusion barriers in cells. Here we show that Septin 7 acts as a ‘molecular brake’ on activation of Orai channels in Drosophila neurons. Lowering Se...

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Detalles Bibliográficos
Autores principales: Deb, Bipan Kumar, Pathak, Trayambak, Hasan, Gaiti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894974/
https://www.ncbi.nlm.nih.gov/pubmed/27225060
http://dx.doi.org/10.1038/ncomms11751

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894974/
https://www.ncbi.nlm.nih.gov/pubmed/27225060
http://dx.doi.org/10.1038/ncomms11751

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