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Prolactin Rescues Immature B-Cells from Apoptosis Induced by B-Cell Receptor Cross-Linking

Prolactin has an immunomodulatory effect and has been associated with B-cell-triggered autoimmune diseases, such as systemic lupus erythematosus (SLE). In mice that develop SLE, the PRL receptor is expressed in early bone marrow B-cells, and increased levels of PRL hasten disease manifestations, whi...

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Detalles Bibliográficos
Autores principales: Flores-Fernández, Rocio, Blanco-Favela, Francisco, Fuentes-Pananá, Ezequiel M., Chávez-Sánchez, Luis, Gorocica-Rosete, Patricia, Pizaña-Venegas, Alberto, Chávez-Rueda, Adriana Karina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894992/
https://www.ncbi.nlm.nih.gov/pubmed/27314053
http://dx.doi.org/10.1155/2016/3219017