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Prolactin Rescues Immature B-Cells from Apoptosis Induced by B-Cell Receptor Cross-Linking
Prolactin has an immunomodulatory effect and has been associated with B-cell-triggered autoimmune diseases, such as systemic lupus erythematosus (SLE). In mice that develop SLE, the PRL receptor is expressed in early bone marrow B-cells, and increased levels of PRL hasten disease manifestations, whi...
Autores principales: | Flores-Fernández, Rocio, Blanco-Favela, Francisco, Fuentes-Pananá, Ezequiel M., Chávez-Sánchez, Luis, Gorocica-Rosete, Patricia, Pizaña-Venegas, Alberto, Chávez-Rueda, Adriana Karina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894992/ https://www.ncbi.nlm.nih.gov/pubmed/27314053 http://dx.doi.org/10.1155/2016/3219017 |
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