Modeling Alzheimer's Disease with Induced Pluripotent Stem Cells: Current Challenges and Future Concerns

Alzheimer's disease (AD) is the most prevalent type of dementia and its pathology is characterized by deposition of extracellular β-amyloid plaques, intracellular neurofibrillary tangles, and extensive neuron loss. While only a few familial AD cases are due to mutations in three causative genes...

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Detalles Bibliográficos
Autores principales: Zhang, Weiwei, Jiao, Bin, Zhou, Miaojin, Zhou, Tao, Shen, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895035/
https://www.ncbi.nlm.nih.gov/pubmed/27313629
http://dx.doi.org/10.1155/2016/7828049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895035/
https://www.ncbi.nlm.nih.gov/pubmed/27313629
http://dx.doi.org/10.1155/2016/7828049

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