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Modeling Alzheimer's Disease with Induced Pluripotent Stem Cells: Current Challenges and Future Concerns
Alzheimer's disease (AD) is the most prevalent type of dementia and its pathology is characterized by deposition of extracellular β-amyloid plaques, intracellular neurofibrillary tangles, and extensive neuron loss. While only a few familial AD cases are due to mutations in three causative genes...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi Publishing Corporation
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895035/ https://www.ncbi.nlm.nih.gov/pubmed/27313629 http://dx.doi.org/10.1155/2016/7828049 |