A dual molecular analogue tuner for dissecting protein function in mammalian cells

Loss-of-function studies are fundamental for dissecting gene function. Yet, methods to rapidly and effectively perturb genes in mammalian cells, and particularly in stem cells, are scarce. Here we present a system for simultaneous conditional regulation of two different proteins in the same mammalia...

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Detalles Bibliográficos
Autores principales: Brosh, Ran, Hrynyk, Iryna, Shen, Jessalyn, Waghray, Avinash, Zheng, Ning, Lemischka, Ihor R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895048/
https://www.ncbi.nlm.nih.gov/pubmed/27230261
http://dx.doi.org/10.1038/ncomms11742

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895048/
https://www.ncbi.nlm.nih.gov/pubmed/27230261
http://dx.doi.org/10.1038/ncomms11742

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